Compounds > hydroxyl radical
Page last updated: 2024-09-04

hydroxyl radical and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

hydroxyl radical has been researched along with (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid in 8 studies

Compound Research Comparison

Studies
(hydroxyl radical)		Trials
(hydroxyl radical)		Recent Studies (post-2010)
(hydroxyl radical)		Studies
((3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid)		Trials
((3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid)		Recent Studies (post-2010) ((3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid)
10,147263,6571,459368396

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoshi, K; Ichihara, K; Yamamoto, A1
Narita, H; Odawara, A; Suzuki, T; Suzumura, K; Tanaka, K; Yasuhara, M1
Obata, T; Yamanaka, Y1
Ebihara, A; Obata, T; Yamanaka, Y2
Obata, T1
Aomine, M; Obata, T; Yonemoti, H1
Jia, Z; Li, Y; Misra, HP; Vandjelovic, N; Zhu, H; Zimmerman, RP1

Other Studies

8 other study(ies) available for hydroxyl radical and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
Fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, scavenges free radicals and inhibits lipid peroxidation in rat liver microsomes.
    European journal of pharmacology, 1998, Nov-13, Volume: 361, Issue:1

    Topics: Animals; Anticholesteremic Agents; Antioxidants; Butylated Hydroxytoluene; Cytochrome P-450 Enzyme System; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipid Peroxidation; Male; Microsomes, Liver; Pravastatin; Probucol; Rats; Rats, Sprague-Dawley; Superoxides

1998
An in vitro study of the hydroxyl radical scavenging property of fluvastatin, and HMG-CoA reductase inhibitor.
    Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:7

    Topics: Biotransformation; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Humans; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Thiourea; Vitamin E

1999
Protective effect of fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on MPP(+)-induced hydroxyl radical in the rat striatum.
    Brain research, 2000, Mar-31, Volume: 860, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Copper; Corpus Striatum; Dopamine; Extracellular Space; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipoproteins, LDL; Male; Microdialysis; Monoamine Oxidase; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Oxidation-Reduction; Rats; Rats, Wistar

2000
Fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, resists hydroxyl radical generation in the rat myocardium.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:4

    Topics: Animals; Copper; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microdialysis; Myocardium; Rats; Rats, Wistar; Time Factors; Tyramine

2000
Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heart.
    Biochimica et biophysica acta, 2001, Apr-30, Volume: 1536, Issue:1

    Topics: Animals; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Heart; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microdialysis; Models, Chemical; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Wistar

2001
Protective effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on copper-induced hydroxyl radical generation in the rat heart.
    Toxicology, 2006, Jun-15, Volume: 223, Issue:3

    Topics: Animals; Cardiotonic Agents; Copper; Dose-Response Relationship, Drug; Extracellular Fluid; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microdialysis; Myocardium; Rats; Rats, Wistar

2006
The protective effect of fluvastatin on hydroxyl radical generation by inhibiting low-density lipoprotein (LDL) oxidation in the rat myocardium.
    Microvascular research, 2009, Volume: 77, Issue:2

    Topics: Animals; Antioxidants; Atherosclerosis; Catechols; Copper; Fatty Acids, Monounsaturated; Fluvastatin; Heart; Hydroxybenzoates; Hydroxyl Radical; Indoles; Lipoproteins, LDL; Male; Microdialysis; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar

2009
EPR studies on hydroxyl radical-scavenging activities of pravastatin and fluvastatin.
    Molecular and cellular biochemistry, 2012, Volume: 364, Issue:1-2

    Topics: DNA Breaks; Electron Spin Resonance Spectroscopy; Fatty Acids, Monounsaturated; Ferrous Compounds; Fluvastatin; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Plasmids; Pravastatin; Reactive Oxygen Species; Spin Trapping

2012